THE ANTI-RELAPSE TREATMENT OF MALARIA.

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Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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The Impact of IL-18 and IFN-γ on Severity of Malaria and Quality of Treatment

Background & Objective: In human malaria, genotype of cytokines affect immune system. The impact of genotype -137G/C in IL-18 and +874A/T in IFN-γ on the severity of malaria and the quality of treatment – as factors to form asymptomatic persons in endemic regions- has been investigated.Materials & Methods: 100 patients and 102 healthy persons were evaluated by Nested-PCR and thick blood fil...

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ژورنال

عنوان ژورنال: The Lancet

سال: 1920

ISSN: 0140-6736

DOI: 10.1016/s0140-6736(01)29448-3